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Faculty of Biology, Chemistry & Earth Sciences

Biochemistry I – Prof. Dr. Clemens Steegborn vertreten durch Prof. Dr. Ulrich Krauß

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Signaling mechanisms in aging and disease – from proteins to targets to drugs

Many molecular details of aging, as a fundamental process in life, and of aging-associated diseases are still poorly understood. We study mechanistic details of function, regulation, and pharmacological modulation of metabolic sensor proteins, which have been found to play key roles in regular metabolism but also in aging processes and the pathophysiology of aging-related diseases. We study these proteins and their interactions using structural and biochemical techniques, and we aim to develop small molecule modulators for these systems as chemical tools and as lead compounds for drug development. 

In particular, we work on three cellular signaling and sensing systems:

Research Group of Prof. Steegborn

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